Immunomodulatory Role of the Clock during Skeletal Muscle Regeneration via Hypoxic NAD+ Production.
Zhu P, Pfrender EM, Steffeck AWT, Zhou Y, Thakkar AV, Gupta NR, Willbanks A, Roy I, Lieber RL, Reczek CR, Chandel NS, Peek CB. Submitted
Circadian timing of satellite cell function and muscle regeneration.
Zhu P, Peek CB. Curr Top Dev Biol (2024) 158:307-339
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PMID: 38670711
Circadian clocks in ageing. In book: Chronobiology and Chronomedicine: From Molecular and Cellular Mechanisms to Whole Body Interdigitating Networks.
Zhu P, Peek CB. Royal Soc. Chem. (2024)
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Mitchondria regulate proliferation in adult cardiac myocytes.
Waypa GB, Smith KA, Mungai PT, Dudley VJ, Helmin KA, Singer BD, Peek CB, Bass J, Beussink-Nelson L, Shah SJ, Ofman G, Wasserstrom JA, Muller WA, Misharin AV, Budinger GRS, Abdala-Valencia H, Chandel NS, Dokic D, Bartom ET, Zhang S, Tatekoshi Y, Mahmoodzadeh A, Ardehali H, Thorp EB, Schumacker PT. J. Clin Invest (2024) Online ahead of print.
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PMID: 38722697
Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids.
Wintzinger M, Panta M, Miz M, Prabakaran AD, Durumutla HB, Sargent M, Peek CB, Bass J, Molkentin JD, Quattrocelli M. Mol Metabolism (2022)
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PMID: 35717025
Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α.
Quattrocelli M, Wintzinger M, Miz K, Levine DC, Peek CB, Bass J, McNally EM. Sci. Advances. (2022) 8(7):eabm1189
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PMID: 35179955
BMAL1 drives muscle repair through control of hypoxic NAD+ regeneration in satellite cells.
Zhu P, Hamlish NX, Thakkar AV, Steffeck AWT, Rendleman EJ, Khan NH, Waldeck NJ, DeVilbiss AW, Martin-Sandoval MS, Mathews TP, Chandel NS, Peek CB. Genes Dev. 2022 Feb 3.
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PMID: 35115380
NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding.
Levine DC, Kuo HY, Hong HK, Cedernaes J, Hepler C, Wright AG, Sommars MA, Kobayashi Y, Marcheva B, Gao P, Ilkayeva OR, Omura C, Ramsey KM, Newgard CB, Barish GD, Peek CB, Chandel NS, Mrksich M, Bass J. Nat Metab. 2021 Dec;3(12):1621-1632. doi: 10.1038/s42255-021-00498-1.
PMID: 34903884
Associations of Poly (ADP-Ribose) Polymerase1 abundance in calf skeletal muscle with walking performance in peripheral artery disease.
Saini SK, Li L, Peek CB, Kosmac K, Polonsky TS, Tian L, Criqui MH, Ferrucci L, Guralnik JM, Kibbe M, Sufit RL, Leeuwenburgh C, McDermott MM.Exp Gerontol. 2020 Oct 15;140:111048. doi: 10.1016/j.exger.2020.111048. PMID: 32755612
Metabolic Implications of Circadian-HIF Crosstalk. Peek CB.Trends Endocrinol Metab. 2020 Jun;31(6):459-468. doi: 10.1016/j.tem.2020.02.008. PMID: 32396846
NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging.
Levine DC, Hong H, Weidemann BJ, Ramsey KM, Affinati AH, Schmidt MS, Cedernaes J, Omura C, Braun R, Lee C, Brenner C, Peek CB, Bass J.Mol Cell. 2020 Jun 4;78(5):835-849.e7.
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Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming
Quattrocelli M, Zelikovich AS, Jiang Z, Peek CB, Demonbreun AR, Kuntz NL, Barish GD, Haldar SM, Bass J, McNally EM
JCI Insight. 2019 Dec; 4(24):
https://doi.org/10.1172/jci.insight.132402
PMID: 31852847
Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism
Rizzini L, Levine DC, Perelis M, Bass J, Peek CB, Pagano M
Current Biology. 2019 Jun; 29(12): 1954-1962.e4.
https://doi.org/10.1016/j.cub.2019.04.073
PMID: 31155351 ISSN: 0960-9822
Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron
Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, Mokadem M, Ahima RS, Bass J
Cell Metabolism. 2019 May; 29(5): 1078-1091.e5.
https://doi.org/10.1016/j.cmet.2019.01.023
PMID: 30827863 ISSN: 1550-4131
ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes.
Wei J, Yuan Y, Chen L, Xu Y, Zhang Y, Wang Y, Yang Y, Peek CB, Diebold L, Gao B, Jin C, Melo-Cardenas J, Chandel NS, Zhang DD, Pan H, Zhang K, Wang J, He F, Fang D,
Nature communications. 2018 Dec; 9(1): doi:https://doi.org/10.1038/s41467-018-06091-7.
PMID: 30201971 PMCID: 30201971 ISSN: 2041-1723
Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle
Peek CB, Levine DC, Cedernaes J, Taguchi A, Kobayashi Y, Tsai SJ, Bonar NA, McNulty MR, Ramsey KM, Bass J,
Cell Metabolism. 2017 Jan 10; 25(1): 86-92. doi:https://doi.org/10.1016/j.cmet.2016.09.010.
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Pancreatic b cell enhancers regulate rhythmic transcription of genes controlling insulin secretion
Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, Hong H, Huang W, Omura C, Allred AL, Bradfield CA, Dinner AR, Barish GD, Bass J,
Science. 2015 Nov 6; 350(6261): doi:https://doi.org/10.1126/science.aac4250.
PMID: 26542580 PMCID: 26542580 ISSN: 0036-8075
Circadian regulation of cellular physiology
Peek CB, Ramsey KM, Levine DC, Marcheva B, Perelis M, Bass J,
Methods in Enzymology. 2015 Jan; 552: 165-184. doi:https://doi.org/10.1016/bs.mie.2014.10.006.
PMID: 25707277 PMCID: 25707277 ISSN: 0076-6879
Circadian clocks and metabolism.
Marcheva B, Ramsey KM, Peek CB, Affinati A, Maury E, Bass J,
Handbook of Experimental Pharmacology. 2013 Jul 26; (217): 127-155.
PMID: 23604478 PMCID: 23604478 ISSN: 0171-2004
ROS-mediated PARP activity undermines mitochondrial function after permeability transition pore opening during myocardial ischemia-reperfusion.
Schriewer JM, Peek CB, Bass J, Schumacker PT,
Journal of the American Heart Association. 2013 Apr; 2(2): doi:https://doi.org/10.1161/JAHA.113.000159.
PMID: 23598272 PMCID: 23598272 ISSN: 2047-9980
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J,
Science. 2013 Jan; 342(6158): doi:https://doi.org/10.1126/science.1243417.
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Nutrient sensing and the circadian clock
Peek CB, Ramsey KM, Marcheva B, Bass J,
Trends in Endocrinology and Metabolism. 2012 Jul; 23(7): 312-318. doi:https://doi.org/10.1016/j.tem.2012.02.003.
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Sterol regulatory element binding proteins in fungi: Hypoxic transcription factors linked to pathogenesis
Bien CM, Espenshade PJ,
Eukaryotic Cell. 2010 Mar; 9(3): 352-359. doi:https://doi.org/10.1128/EC.00358-09.
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Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in cryptococcus neoformans
Chang YC, Ingavale SS, Bien C, Espenshade P, Kwon-Chung KJ,
Eukaryotic Cell. 2009 Nov; 8(11): 1770-1779. doi:https://doi.org/10.1128/EC.00207-09.
PMID: 19749173 PMCID: 19749173 ISSN: 1535-9778
Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs
Bien CM, Chang YC, Nes WD, Kwon-Chung KJ, Espenshade PJ,
Molecular Microbiology. 2009 Nov; 74(3): 672-690. doi:https://doi.org/10.1111/j.1365-2958.2009.06895.x.
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4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress
Hughes AL, Lee CYS, Bien CM, Espenshade PJ,
Journal of Biological Chemistry. 2007 Aug 17; 282(33): 24388-24396. doi:https://doi.org/10.1074/jbc.M701326200.
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Cobalt chloride, a hypoxia-mimicking agent, targets sterol synthesis in the pathogenic fungus Cryptococcus neoformans
Lee H, Bien CM, Hughes AL, Espenshade PJ, Kwon-Chung KJ, Chang YC,
Molecular Microbiology. 2007 Aug; 65(4): 1018-1033. doi:https://doi.org/10.1111/j.1365-2958.2007.05844.x.
PMID: 17645443 ISSN: 0950-382X
Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans
Chang YC, Bien CM, Lee H, Espenshade PJ, Kwon-Chung KJ,
Molecular Microbiology. 2007 May; 64(3): 614-629. doi:https://doi.org/10.1111/j.1365-2958.2007.05676.x.
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